| May 13, 2022 | “Doctor Strange in the Multiverse of Madness” | $61,755,804 | DIS |
| May 6, 2022 | “Doctor Strange in the Multiverse of Madness” | $187,420,998 | DIS |
| April 29, 2022 | “The Bad Guys” | $16,237,070 | UNI |
| April 22, 2022 | “The Bad Guys” | $23,950,245 | UNI |
| April 15, 2022 | “Fantastic Beasts: The Secrets of Dumbledore” | $42,151,256 | WB |
| April 8, 2022 | “Sonic the Hedgehog 2” | $72,105,176 | PAR |
| April 1, 2022 | “Morbius” | $39,005,895 | SON |
| March 25, 2022 | “The Lost City” | $30,453,269 | PAR |
| March 18, 2022 | “The Batman” | $36,723,197 | WB |
| March 11, 2022 | “The Batman” | $66,511,221 | WB |
| March 4, 2022 | “The Batman” | $134,008,624 | WB |
| February 25, 2022 | “Uncharted” | $23,001,773 | SON |
| February 18, 2022 | “Uncharted” | $44,010,155 | SON |
| February 11, 2022 | “Death on the Nile” | $12,891,123 | 20TH |
| February 4, 2022 | “Jackass Forever” | $23,154,388 | PAR |
| January 28, 2022 | “Spider-Man: No Way Home” | $11,003,528 | SON |
| January 21, 2022 | “Spider-Man: No Way Home” | $14,005,614 | SON |
| January 14, 2022 | “Scream” | $30,018,805 | PAR |
| January 7, 2022 | “Spider-Man: No Way Home” | $32,617,921 | SON |
